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Oxidative stress plays a critical role in the pathogenesis of Parkinsons disease

StatPearls [Internet], 2023 June Takaaki Sugihara, Masahiko Koda, Toshiaki Okamoto, Kenichi Miyoshi, Tomomitsu Matono, Kenji Oyama, Keiko Hosho, Jun-ichi Okano, Hajime Isomoto, Yoshikazu Murawaki

Published clinical trials used continuous daily administration for 12-24 weeks without scheduled breaks, establishing this as a viable approach with maintained safety throughout the treatment period

Brain and Behavior , 10 (8)

Therefore, GABAergic/glutamatergic transmission, which involves inhibitory and excitatory neurotransmitters in the brain, can be targeted for MS treatment [15]